产品货号：
Z27054
中文名称：
SMAD1/2/3/5抗体
英文名称：
Anti-SMAD1/2/3/5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SMAD1/2/3/5 Antibody |
| 指标别名 | BSP 1;BSP1;hSMAD1;JV4 1;JV41;MAD homolog 1;Mad related protein 1;MADH1;MADR1;Mothers against DPP homolog 1;SMAD 1;SMAD family member 1;SMAD1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rabbit,rat |
| 应用范围 | IHC |
| 基因名称 | SMAD1/SMAD2/SMAD3/SMAD5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human SMAD 1/2/3/5(442-456aa GPLQWLDKVLTQMGS),identical to the related mouse and rat sequences. |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SMADs are proteins that modulate the activity of transforming growth factor beta ligands.The SMADs,often in complex with other SMADs/CoSMAD,act as transcription factors that regulate the expression of certain genes.Zhu,H et al concluded that targeted ubiquitination of SMADs may serve to control both embryonic development and a wide variety of cellular responses to TGF-beta signals.R-Smads or receptor regulated Smads are a class of proteins that include SMAD1,SMAD2,SMAD3,SMAD5,and SMAD8.In response to signals by the TGF-beta superfamily of ligands these proteins associate with receptor kinases and are phosphorylated at an SSXS motif at their extreme C-terminus.These proteins then typically bind to the common mediator Smad or co-SMAD SMAD4. |
| Uniprot ID | Q15797/Q15796/P84022/Q99717 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | SMAD family member 1/2/3/5 |
| 蛋白名全称 | Mothers against decapentaplegic homolog 1/2/3/5 |
| 推荐稀释比 | Immunohistochemistry in paraffin section IHC-(P) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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